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SURP And G Patch Domain Containing Protein 2 (SUGP2)

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SFRS14; Splicing Factor,Arginine/Serine-Rich 14; Arginine/serine-rich-splicing factor 14

SURP And G Patch Domain Containing Protein 2 (SUGP2)
CCC K349
HGNC 18641
MGI 2678085
PubMed 12594045
RGD 1306042
UniProt Q8IX01
Wiki SUGP2
SFRS14 encodes a deduced 1,083-amino acid protein with an estimated molecular mass of 120.2 kD. Both SF4 and SFRS14 contain 2 SURP motifs and a single G-patch domain in their C termini. SFRS14 also contains an arginine/serine-rich N terminus, suggesting that it is a novel member of the SR-related family of pre-mRNA processing factors. The mouse Sfrs14 protein shares an identical domain organization and 73% sequence identity with its human counterpart. RT-PCR identified SFRS14 expression in adult skeletal muscle and brain.SFRS14 gene contains 12 exons and spans 41.2 kb. SFRS14 undergoes alternative 3-prime end processing. The largest SFRS14 transcript lacks exon 11, which constitutes the first 103 basepairs of the 3-prime UTR.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SURP And G Patch Domain Containing Protein 2 (SUGP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SURP And G Patch Domain Containing Protein 2 (SUGP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SURP And G Patch Domain Containing Protein 2 (SUGP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SURP And G Patch Domain Containing Protein 2 (SUGP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for SURP And G Patch Domain Containing Protein 2 (SUGP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SURP And G Patch Domain Containing Protein 2 (SUGP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SURP And G Patch Domain Containing Protein 2 (SUGP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SURP And G Patch Domain Containing Protein 2 (SUGP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SURP And G Patch Domain Containing Protein 2 (SUGP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for SURP And G Patch Domain Containing Protein 2 (SUGP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SURP And G Patch Domain Containing Protein 2 (SUGP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SURP And G Patch Domain Containing Protein 2 (SUGP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SURP And G Patch Domain Containing Protein 2 (SUGP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SURP And G Patch Domain Containing Protein 2 (SUGP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for SURP And G Patch Domain Containing Protein 2 (SUGP2) ELISA Kit Customized Service Offer
  1. "SF4 and SFRS14, two related putative splicing factors on human chromosome 19p13.11."Gene 305:91-100(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Solution structure of SURP domain in SFRS14 protein."Submitted (NOV-2005) to the PDB data bank