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Mastermind Like Protein 3 (MAML3)

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TNRC3; MAM2; CAGH3; GDN; Mastermind(drosophila)Like 3; Trinucleotide Repeat Containing 3

Mastermind Like Protein 3 (MAML3)
CCC K346
HGNC 16272
MGI 2389461
PubMed 22069191
RGD 1308177
UniProt Q96JK9
MAML3 contains 1,162 amino acids. RT-PCR ELISA detected high expression in ovary, with moderate to high expression in all other adult and fetal tissues and specific adult brain regions examined.The deduced 1,133-amino acid MAML3 protein has a calculated molecular mass of 115 kD. All 3 MAML proteins contain a conserved N-terminal basic domain, but the rest of the sequences are rather divergent. In addition, all 3 are proline- and glutamine-rich, and MAML2 and MAML3 contain several glutamine stretches. Northern blot analysis detected wide expression of MAML2 and MAML3 transcripts of about 7.5 kb. Fluorescence-tagged MAML proteins were expressed in a speckled nuclear staining pattern in transfected COS-7 and osteosarcoma cells, with considerable heterogeneity in the size of the dots.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mastermind Like Protein 3 (MAML3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mastermind Like Protein 3 (MAML3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mastermind Like Protein 3 (MAML3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mastermind Like Protein 3 (MAML3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mastermind Like Protein 3 (MAML3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mastermind Like Protein 3 (MAML3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mastermind Like Protein 3 (MAML3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mastermind Like Protein 3 (MAML3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mastermind Like Protein 3 (MAML3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mastermind Like Protein 3 (MAML3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mastermind Like Protein 3 (MAML3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mastermind Like Protein 3 (MAML3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mastermind Like Protein 3 (MAML3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mastermind Like Protein 3 (MAML3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mastermind Like Protein 3 (MAML3) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract].
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification of new human mastermind proteins defines a family that consists of positive regulators for Notch signaling."J. Biol. Chem. 277:50612-50620(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors."Mol. Cell. Biol. 22:7688-7700(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]