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Bromodomain And WD Repeat Containing Protein 1 (BRWD1)

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N143; WDR9; C21orf107; WD repeat-containing protein 9

Bromodomain And WD Repeat Containing Protein 1 (BRWD1)
CCC K291
HGNC 12760
MGI 1890651
PubMed 18353305
RGD 1309030
UniProt Q9NSI6
Wiki BRWD1
BRWD1 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain And WD Repeat Containing Protein 1 (BRWD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain And WD Repeat Containing Protein 1 (BRWD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain And WD Repeat Containing Protein 1 (BRWD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain And WD Repeat Containing Protein 1 (BRWD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain And WD Repeat Containing Protein 1 (BRWD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain And WD Repeat Containing Protein 1 (BRWD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain And WD Repeat Containing Protein 1 (BRWD1) ELISA Kit Customized Service Offer
  1. "Characterisation and expression analysis of the WDR9 gene, located in the Down critical region-2 of the human chromosome 21."Biochim. Biophys. Acta 1577:377-383(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 21." Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "High resolution physical mapping and identification of transcribed sequences in the Down syndrome region-2."Biochem. Biophys. Res. Commun. 243:572-578(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."BMC Biol. 9:54-54(2011) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Histone recognition and large-scale structural analysis of the human bromodomain family."Cell 149:214-231(2012) [PubMed] [Europe PMC] [Abstract]