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Jumonji Domain Containing Protein 1C (JMJD1C)

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TRIP8; Thyroid Hormone Receptor Interactor 8; Probable JmjC domain-containing histone demethylation protein 2C

Jumonji Domain Containing Protein 1C (JMJD1C)
CCC K259
HGNC 12313
MGI 1918614
PubMed 24240613
RGD 708458
UniProt Q15652
The thyroid hormone receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. They must specifically interact with a number of proteins as they progress from their initial translation and nuclear translocation to heterodimerization with retinoid X receptors (RXRs), functional interactions with other transcription factors and the basic transcriptional apparatus, and eventually, degradation.
TRIP8 strongly interacted with rat Thrb only in the presence of thyroid hormone. It also showed a ligand-dependent interaction with RXR-alpha (RXRA), but did not interact with the glucocorticoid receptor (NR3C1) under any condition.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Jumonji Domain Containing Protein 1C (JMJD1C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Jumonji Domain Containing Protein 1C (JMJD1C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Jumonji Domain Containing Protein 1C (JMJD1C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Jumonji Domain Containing Protein 1C (JMJD1C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Jumonji Domain Containing Protein 1C (JMJD1C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Jumonji Domain Containing Protein 1C (JMJD1C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Jumonji Domain Containing Protein 1C (JMJD1C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Jumonji Domain Containing Protein 1C (JMJD1C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Jumonji Domain Containing Protein 1C (JMJD1C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Jumonji Domain Containing Protein 1C (JMJD1C) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Jumonji Domain Containing Protein 1C (JMJD1C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Jumonji Domain Containing Protein 1C (JMJD1C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Jumonji Domain Containing Protein 1C (JMJD1C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Jumonji Domain Containing Protein 1C (JMJD1C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Jumonji Domain Containing Protein 1C (JMJD1C) ELISA Kit Customized Service Offer
  1. "A novel variant of the putative demethylase gene, s-JMJD1C, is a coactivator of the AR."Arch. Biochem. Biophys. 460:56-66(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  6. "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor."Mol. Endocrinol. 9:243-254(1995) [PubMed] [Europe PMC] [Abstract]
  7. "Identification and characterization of TRIP8 gene in silico."Int. J. Mol. Med. 12:817-821(2003) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]