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AT-Rich Interactive Domain Containing Protein 2 (ARID2)

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BAF200; p200; BRG1-associated factor 200; Zinc finger protein with activation potential; Zipzap/p200

AT-Rich Interactive Domain Containing Protein 2 (ARID2)
CCC K257
HGNC 18037
MGI 1924294
PubMed 23047306
RGD 1311105
UniProt Q68CP9
Wiki ARID2
ARID2 is a subunit of the PBAF chromatin-remodeling complex, which facilitates ligand-dependent transcriptional activation by nuclear receptors.RT-PCR ELISA detected ARID2 expression in all tissues and specific brain regions examined, with highest expression in ovary and lowest expression in spinal cord.The human and Drosophila proteins contain an N-terminal ARID domain, followed by several LLxxLL motifs and C-terminal canonical and variant C2H2-type zinc finger motifs.
ARID2 is an integral component of PBAF. ARID2 interacted directly with BAF180 in the absence of DNA. However, ARID2 was able to form a complex in cells lacking BAF180, and suppression of ARID2 by small interfering RNA in these cells reduced both basal and IFN-alpha-induced IFITM1 expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 2 (ARID2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 2 (ARID2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 2 (ARID2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 2 (ARID2) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 2 (ARID2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 2 (ARID2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 2 (ARID2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 2 (ARID2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 2 (ARID2) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 2 (ARID2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 2 (ARID2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 2 (ARID2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 2 (ARID2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 2 (ARID2) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 2 (ARID2) ELISA Kit Customized Service Offer
  1. "Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation."Biochem. Biophys. Res. Commun. 346:794-801(2006) [PubMed] [Europe PMC] [Abstract]
  2. "DNA-binding properties of ARID family proteins."Nucleic Acids Res. 33:66-80(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  11. "Recent advances in understanding chromatin remodeling by SWI/SNF complexes."Curr. Opin. Genet. Dev. 13:136-142(2003) [PubMed] [Europe PMC] [Abstract]
  12. "PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes."Genes Dev. 19:1662-1667(2005) [PubMed] [Europe PMC] [Abstract]