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AT-Rich Interactive Domain Containing Protein 4B (ARID4B)

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BCAA; BRCAA1; RBBP1L1; RBP1L1; SAP180; Retinoblastoma Binding Protein 1-Like 1; 180 kDa Sin3-associated polypeptide; Breast cancer-associated antigen BRCAA1

AT-Rich Interactive Domain Containing Protein 4B (ARID4B)
CCC K252
HGNC 15550
MGI 2137512
PubMed 23487765
RGD 619919
UniProt Q4LE39
Wiki ARID4B
ARID4B encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependent SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 4B (ARID4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 4B (ARID4B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 4B (ARID4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 4B (ARID4B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 4B (ARID4B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 4B (ARID4B) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 4B (ARID4B) ELISA Kit Customized Service Offer
  1. "RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis."J. Natl. Cancer Inst. 93:1159-1165(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and characterization of three new components of the mSin3A corepressor complex."Mol. Cell. Biol. 23:3456-3467(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of BRCAA1 and its novel antigen epitope identification."Cancer Epidemiol. Biomarkers Prev. 13:1136-1145(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]