Non Metastatic Cells 3, Protein NM23A Expressed In (NME3)

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DR-nm23; NDK3; NDPKC; Nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C

Non Metastatic Cells 3, Protein NM23A Expressed In (NME3)
DR-nm23 mRNA was preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, resulted in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and caused apoptotic cell death.The deduced 169-amino acid protein shares 88% identity with human NME3. Northern blot analysis of several mouse tissues detected a 0.9-kb transcript expressed at highest levels in liver and kidney, with moderate levels in heart, brain, spleen, and lung. Little to no expression was detected in other mouse tissues examined. In situ hybridization of 15-day postcoitum mouse embryos showed expression in nervous tissue and thymus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK243Hu01 Recombinant Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAK243Hu01 Polyclonal Antibody to Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) WB,IHC
Assay Kits SEK243Hu ELISA Kit for Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPK243Mu01 Recombinant Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAK243Mu01 Polyclonal Antibody to Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Non Metastatic Cells 3, Protein NM23A Expressed In (NME3) ELISA Kit Customized Service Offer
  1. "Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells."Proc. Natl. Acad. Sci. U.S.A. 92:7435-7439(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]