≡

RAN Binding Protein 9 (RANBP9)

[Edit]

BPM-L; BPM90; RanBP7; RANBPM; Ran Binding Protein In the Microtubule Organizing Center

RAN Binding Protein 9 (RANBP9)
CCC K237
HGNC 13727
MGI 1928741
PubMed 22294787
UniProt Q96S59
Wiki RANBP9
RANBP9encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11.
The cDNA is 2.8 kb in length and encodes a protein of 500 amino acid residues. Mouse, hamster, and human RANBPM are identical. The C-terminal half of the S. cerevisiae gene YGL227w is 30% identical to RANBPM. Immunoblotting analysis using antibodies against RANBPM revealed that RANBPM was localized within the centrosome throughout the cell cycle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 9 (RANBP9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 9 (RANBP9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 9 (RANBP9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 9 (RANBP9) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 9 (RANBP9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 9 (RANBP9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 9 (RANBP9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 9 (RANBP9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 9 (RANBP9) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 9 (RANBP9) ELISA Kit Customized Service Offer
  1. "Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex."Gene 272:25-33(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin."J. Cell Biol. 143:1041-1052(1998) [PubMed] [Europe PMC] [Abstract]
  6. "HIPK2 associates with RanBPM."Biochem. Biophys. Res. Commun. 297:148-153(2002) [PubMed] [Europe PMC] [Abstract]
  7. "RanBPM, a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor."J. Biol. Chem. 277:48020-48027(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM."Biochem. J. 367:87-95(2002) [PubMed] [Europe PMC] [Abstract]
  9. "RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer."BMC Cancer 2:28-28(2002) [PubMed] [Europe PMC] [Abstract]
  10. "Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM."J. Biol. Chem. 277:36216-36222(2002) [PubMed] [Europe PMC] [Abstract]
  11. "Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy."Biochem. Biophys. Res. Commun. 303:1186-1192(2003) [PubMed] [Europe PMC] [Abstract]
  12. "The cyclin-dependent kinase 11(p46) isoform interacts with RanBPM."Biochem. Biophys. Res. Commun. 310:14-18(2003) [PubMed] [Europe PMC] [Abstract]
  13. "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM."Gene 303:47-54(2003) [PubMed] [Europe PMC] [Abstract]
  14. "Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M."J. Biol. Chem. 278:49573-49581(2003) [PubMed] [Europe PMC] [Abstract]
  15. "A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling."Biochem. Biophys. Res. Commun. 313:320-326(2004) [PubMed] [Europe PMC] [Abstract]
  16. "RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1."J. Biol. Chem. 279:13027-13034(2004) [PubMed] [Europe PMC] [Abstract]
  17. "The C-terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre."J. Mol. Biol. 343:43-53(2004) [PubMed] [Europe PMC] [Abstract]
  18. "Protein stability and function of p73 are modulated by a physical interaction with RanBPM in mammalian cultured cells."Oncogene 24:938-944(2005) [PubMed] [Europe PMC] [Abstract]
  19. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  20. "RanBP10 acts as a novel coactivator for the androgen receptor."Biochem. Biophys. Res. Commun. 368:121-125(2008) [PubMed] [Europe PMC] [Abstract]
  21. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  22. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  23. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  24. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]