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Homeobox Protein A9 (HOXA9)

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HOX1; ABD-B; HOX1.7; HOX1G

Homeobox Protein A9 (HOXA9)
CCC K200
HGNC 5109
MGI 96180
PubMed 22945634
RGD 1587253
UniProt P31269
Wiki HOXA9
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.
HOXA9 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Homeobox Protein A9 (HOXA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Homeobox Protein A9 (HOXA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Homeobox Protein A9 (HOXA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Homeobox Protein A9 (HOXA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Homeobox Protein A9 (HOXA9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Homeobox Protein A9 (HOXA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Homeobox Protein A9 (HOXA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Homeobox Protein A9 (HOXA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Homeobox Protein A9 (HOXA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Homeobox Protein A9 (HOXA9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Homeobox Protein A9 (HOXA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Homeobox Protein A9 (HOXA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Homeobox Protein A9 (HOXA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Homeobox Protein A9 (HOXA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Homeobox Protein A9 (HOXA9) ELISA Kit Customized Service Offer
  1. "Endothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9."J. Biol. Chem. 274:1415-1422(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9."Nat. Genet. 12:159-167(1996) [PubMed] [Europe PMC] [Abstract]
  5. "The human HOX gene family."Nucleic Acids Res. 17:10385-10402(1989) [PubMed] [Europe PMC] [Abstract]
  6. "A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23)."Cancer Res. 63:1202-1206(2003) [PubMed] [Europe PMC] [Abstract]
  7. "HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules."Mol. Cell. Biol. 32:1202-1213(2012) [PubMed] [Europe PMC] [Abstract]