![Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1)](/upload/item/img/Fragile-X-Mental-Retardation-Syndrome-Related-Protein-1-(FXR1)-99164.jpg)
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
This cDNA was then used to screen a HeLa cell library. They identified a cDNA that encodes a predicted protein of 621 amino acids. The gene, designated FXR1 (FMR1 cross-reacting relative) by them, shows 86% amino acid sequence identity to the KH RNA binding domains of FMR1 and 70% identity over the amino-terminal domain. However, the carboxyl domains are entirely unrelated. RT-PCR analysis showed that many cell types express FXR1 mRNA.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPK164Ra01 | Recombinant Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAK164Ra01 | Polyclonal Antibody to Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fragile X Mental Retardation Syndrome Related Protein 1 (FXR1) | ELISA Kit Customized Service Offer |
- "FXR1, an autosomal homolog of the fragile X mental retardation gene."EMBO J. 14:2401-2408(1995) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]