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RNA Polymerase II, DNA Directed Polypeptide J (POLR2J)

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POLR2J1; RPB11; RPB11A; RPB11m; hRPB14; RNA polymerase II 13.3 kDa subunit; DNA-directed RNA polymerase II subunit RPB11-a

RNA Polymerase II, DNA Directed Polypeptide J (POLR2J)
CCC K153
HGNC 9197
MGI 109582
PubMed 15586814
RGD 1310198
UniProt P52435
Wiki POLR2J
POLR2J encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.
The predicted 117-amino acid human protein is 52% identical to yeast RPB11. Human RPB11 contains a conserved 18-amino acid region that is present in other RNA polymerase subunits and which may be involved in interactions among the subunits during assembly of the complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II, DNA Directed Polypeptide J (POLR2J) ELISA Kit Customized Service Offer
  1. "Cloning of a novel human RNA polymerase II subunit downregulated by doxorubicin: new potential mechanisms of drug related toxicity."FEBS Lett. 384:48-52(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Interactions between the human RNA polymerase II subunits."J. Biol. Chem. 272:16815-16821(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]