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SIX Homeobox Protein 4 (SIX4)

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AREC3; Sine Oculis Homeobox Homolog 4

SIX Homeobox Protein 4 (SIX4)
CCC K009
HGNC 10890
MGI 106034
PubMed 23987514
RGD 1306726
UniProt Q9UIU6
Wiki SIX4
SIX4 encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. The genomic coordinates used for the transcript record were based on transcript alignments.
Human SIX4 encodes a 781-amino acid protein that shares 90% overall sequence identity and 100% identity within the Six domain and the homeodomain with its mouse counterpart, indicating that the proteins share the same DNA-binding specificity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SIX Homeobox Protein 4 (SIX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SIX Homeobox Protein 4 (SIX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SIX Homeobox Protein 4 (SIX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SIX Homeobox Protein 4 (SIX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for SIX Homeobox Protein 4 (SIX4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SIX Homeobox Protein 4 (SIX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SIX Homeobox Protein 4 (SIX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SIX Homeobox Protein 4 (SIX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SIX Homeobox Protein 4 (SIX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for SIX Homeobox Protein 4 (SIX4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SIX Homeobox Protein 4 (SIX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SIX Homeobox Protein 4 (SIX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SIX Homeobox Protein 4 (SIX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SIX Homeobox Protein 4 (SIX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for SIX Homeobox Protein 4 (SIX4) ELISA Kit Customized Service Offer
  1. "Structure and chromosome mapping of the human SIX4 and murine Six4 genes."Cytogenet. Cell Genet. 87:108-112(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative proteomic identification of six4 as the trex-binding factor in the muscle creatine kinase enhancer."Mol. Cell. Biol. 24:2132-2143(2004) [PubMed] [Europe PMC] [Abstract]
  5. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]