MAS Related GPR Member G (MRGPRG)

[Edit]

MRGG; GPR169; G Protein-Coupled Receptor 169; Mas-related G-protein coupled receptor member G

MAS Related GPR Member G (MRGPRG)
Dong et al. (2001) identified, in the mouse and human genomes, a family of G protein-coupled receptors (GPCRs) related to the MAS1 oncogene, including MRGG. Several pseudogenes were also identified. The predicted MRG proteins contain transmembrane, extracellular, and cytoplasmic domains. A subset of MRGs was expressed in specific subpopulations of sensory neurons that detect painful stimuli. The expression patterns of these genes thus revealed an unexpected degree of molecular diversity among nociceptive neurons. Some MRGs could be specifically activated in heterologous cells by RFamide neuropeptides such as NPFF and NPAF, which are analgesic in vivo. The authors concluded that MRGs may regulate nociceptor function and/or development, including the sensation or modulation of pain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAS Related GPR Member G (MRGPRG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAS Related GPR Member G (MRGPRG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAS Related GPR Member G (MRGPRG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAS Related GPR Member G (MRGPRG) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAS Related GPR Member G (MRGPRG) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAS Related GPR Member G (MRGPRG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAS Related GPR Member G (MRGPRG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAS Related GPR Member G (MRGPRG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAS Related GPR Member G (MRGPRG) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAS Related GPR Member G (MRGPRG) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAS Related GPR Member G (MRGPRG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAS Related GPR Member G (MRGPRG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAS Related GPR Member G (MRGPRG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAS Related GPR Member G (MRGPRG) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAS Related GPR Member G (MRGPRG) ELISA Kit Customized Service Offer
  1. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The G protein-coupled receptor repertoires of human and mouse."Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003) [PubMed] [Europe PMC] [Abstract]