Jun D Proto Oncogene (JUND)
[Edit]AP-1; Transcription Factor Jun-D; JunD-FL Isoform; Activator Protein 1
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JUND is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms.JUND is the most broadly expressed member of the JUN family and the AP1 transcription factor complex .
The antiapoptotic role of JUND was confirmed using an in vivo model of TNF-mediated hepatitis. The authors proposed that JUND protects cells from senescence, or apoptotic responses to stress stimuli, by acting as a modulator of the signaling pathways that link RAS to p53.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Jun D Proto Oncogene (JUND) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Jun D Proto Oncogene (JUND) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Jun D Proto Oncogene (JUND) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Jun D Proto Oncogene (JUND) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Jun D Proto Oncogene (JUND) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Jun D Proto Oncogene (JUND) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Jun D Proto Oncogene (JUND) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Jun D Proto Oncogene (JUND) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Jun D Proto Oncogene (JUND) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Jun D Proto Oncogene (JUND) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Jun D Proto Oncogene (JUND) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Jun D Proto Oncogene (JUND) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Jun D Proto Oncogene (JUND) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Jun D Proto Oncogene (JUND) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Jun D Proto Oncogene (JUND) | ELISA Kit Customized Service Offer |
- "Structure and function of human jun-D."Oncogene 6:561-566(1991) [PubMed] [Europe PMC] [Abstract]
- "Isolation of human cDNA clones of jun-related genes, jun-B and jun-D."Nucleic Acids Res. 18:3047-3048(1990) [PubMed] [Europe PMC] [Abstract]
- "Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription."Cell 96:143-152(1999) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]