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GRIP And Coiled Coil Domain Containing Protein 1 (GCC1)

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GCC1P; GCC88; Golgi Coiled-Coil 1

GRIP And Coiled Coil Domain Containing Protein 1 (GCC1)
CCC J898
HGNC 19095
MGI 1921625
PubMed 22158537
UniProt Q96CN9
Wiki GCC1
GCC1 is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport.
The deduced 775-amino acid GCC88 protein has a calculated molecular mass of 88 kD. Both endogenous and fluorescence-tagged GCC88 and GCC185 localized to the trans-Golgi network, and this localization required a functional GRIP domain. Brefeldin A treatment indicated that both GCC88 and GCC185 are peripheral membrane Golgi proteins. Western blot analysis of HeLa cell extracts detected endogenous GCC88 at an apparent molecular mass of 105 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for GRIP And Coiled Coil Domain Containing Protein 1 (GCC1) ELISA Kit Customized Service Offer
  1. "GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network."J. Biol. Chem. 278:4216-4226(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins."Curr. Biol. 9:385-388(1999) [PubMed] [Europe PMC] [Abstract]