F-Box And WD Repeat Domain Containing Protein 8 (FBXW8)
[Edit]FBW6; FBW8; FBX29; FBXO29; F-Box Only Protein 29; F-box and WD-40 domain-containing protein 8; F-box only protein 29
FBXW8 encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for F-Box And WD Repeat Domain Containing Protein 8 (FBXW8) | ELISA Kit Customized Service Offer |
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- "The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1."J. Biol. Chem. 289:4009-4017(2014) [PubMed] [Europe PMC] [Abstract]
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