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Meis Homeobox Protein 1 (MEIS1)

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Myeloid Ecotropic Viral Integration Site 1 Homolog

Meis Homeobox Protein 1 (MEIS1)
CCC J741
HGNC 7000
MGI 104717
PubMed 7565694
UniProt O00470
Wiki MEIS1
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.
MEIS1 encodes a novel homeobox protein belonging to the TALE (three amino acid loop extension) family of homeodomain-containing proteins. The homeodomain of MEIS1 is the only conserved motif within the entire 390-amino acid protein. Meis1 regulates Pbx1 activity by promoting nuclear import of the Pbx1 protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Meis Homeobox Protein 1 (MEIS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Meis Homeobox Protein 1 (MEIS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Meis Homeobox Protein 1 (MEIS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Meis Homeobox Protein 1 (MEIS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Meis Homeobox Protein 1 (MEIS1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Meis Homeobox Protein 1 (MEIS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Meis Homeobox Protein 1 (MEIS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Meis Homeobox Protein 1 (MEIS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Meis Homeobox Protein 1 (MEIS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Meis Homeobox Protein 1 (MEIS1) ELISA Kit Customized Service Offer
  1. "Cloning and mapping of the MEIS1 gene, the human homolog of a murine leukemogenic gene."Genomics 43:99-103(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene."Blood 101:4748-4756(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "MEIS1 p.R272H in familial restless legs syndrome."Neurology 73:243-245(2009) [PubMed] [Europe PMC] [Abstract]