≡

Actin Binding LIM Protein 1 (ABLIM1)

[Edit]

LIMAB1; Limatin; Actin-binding double zinc finger protein

Actin Binding LIM Protein 1 (ABLIM1)
CCC J692
HGNC 78
MGI 1194500
PubMed 21547531
UniProt O14639
Wiki ABLIM1
ABLIM1encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.The ABLIM protein exists in 3 alternatively spliced isoforms, all varying in the number of LIM domains, with widespread tissue distribution. The full-length 778-amino acid protein is found exclusively in the retina and is enriched in biochemical extracts of retinal rod inner segments.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Binding LIM Protein 1 (ABLIM1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Binding LIM Protein 1 (ABLIM1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Binding LIM Protein 1 (ABLIM1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Binding LIM Protein 1 (ABLIM1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Binding LIM Protein 1 (ABLIM1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Binding LIM Protein 1 (ABLIM1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Binding LIM Protein 1 (ABLIM1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Binding LIM Protein 1 (ABLIM1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Binding LIM Protein 1 (ABLIM1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Binding LIM Protein 1 (ABLIM1) ELISA Kit Customized Service Offer
  1. "Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein."J. Cell Biol. 138:575-588(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 1:223-229(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  10. "Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin."J. Biol. Chem. 282:8393-8403(2007) [PubMed] [Europe PMC] [Abstract]
  11. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  12. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  13. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  18. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]