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V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1)

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ABL; JTK7; p150; C-Abl Oncogene 1,Receptor Tyrosine Kinase; Abelson tyrosine-protein kinase 1

V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1)
CCC J691
HGNC 76
MGI 87859
PubMed 24366361
RGD 1584969
UniProt P00519
Wiki ABL
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for V-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) ELISA Kit Customized Service Offer
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