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Acetylcholinesterase Associated Protein (ACHAP)

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CUTA; C6orf82; CutA Divalent Cation Tolerance Homolog; Brain acetylcholinesterase putative membrane anchor

Acetylcholinesterase Associated Protein (ACHAP)
CCC J684
HGNC 21101
MGI 1914925
PubMed 16487640
RGD 1303306
UniProt O60888
CutA is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs.CutA may play a role in anchoring acetylcholinesterase in neuronal cell membranes and may be involved in signal transduction.
CutA is a ubiquitous trimeric protein, homologous to the bacterial CutA1 protein that belongs to an operon involved in resistance to divalent ions ("copper tolerance A"). The function of this protein in plants and animals is unknown, and several hypotheses concerning its subcellular localization have been proposed.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ684Hu01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ684Hu01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
MAJ684Hu21 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
Assay Kits SEJ684Hu ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acetylcholinesterase Associated Protein (ACHAP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acetylcholinesterase Associated Protein (ACHAP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) ELISA Kit Customized Service Offer
  1. "Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization."J. Neurochem. 74:2146-2153(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Two distinct proteins are associated with tetrameric acetylcholinesterase on the cell surface."J. Biol. Chem. 275:34260-34265(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Divalent cation tolerant protein CUTA from Homo sapiens O60888."Submitted (SEP-2004) to the PDB data bank