Activity Dependent Neuroprotector Protein (ADNP)
[Edit]ADNP1; ADNP Homeobox 1; Activity-dependent neuroprotective protein
![Activity Dependent Neuroprotector Protein (ADNP)](/upload/item/img/Activity-Dependent-Neuroprotector-Protein-(ADNP)-98674.jpg)
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells.
Activity Dependent Neuroprotector contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ674Hu01 | Recombinant Activity Dependent Neuroprotector Protein (ADNP) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAJ674Hu01 | Polyclonal Antibody to Activity Dependent Neuroprotector Protein (ADNP) | WB |
MAJ674Hu21 | Monoclonal Antibody to Activity Dependent Neuroprotector Protein (ADNP) | WB; IHC; ICC; IP. | |
Assay Kits | SEJ674Hu | ELISA Kit for Activity Dependent Neuroprotector Protein (ADNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ674Mu01 | Recombinant Activity Dependent Neuroprotector Protein (ADNP) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Activity Dependent Neuroprotector Protein (ADNP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Activity Dependent Neuroprotector Protein (ADNP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Activity Dependent Neuroprotector Protein (ADNP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Activity Dependent Neuroprotector Protein (ADNP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Activity Dependent Neuroprotector Protein (ADNP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Activity Dependent Neuroprotector Protein (ADNP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Activity Dependent Neuroprotector Protein (ADNP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Activity Dependent Neuroprotector Protein (ADNP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Activity Dependent Neuroprotector Protein (ADNP) | ELISA Kit Customized Service Offer |
- "Cloning and characterization of the human activity-dependent neuroprotective protein."J. Biol. Chem. 276:708-714(2001) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
- "NAP and D-SAL: neuroprotection against the beta amyloid peptide (1-42)."BMC Neurosci. 9:S3-S3(2008) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
- "A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP." Nat. Genet. 46:380-384(2014) [PubMed] [Europe PMC] [Abstract]