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Desmoyokin (AHNAK)

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AHNAKRS; AHNAK Nucleoprotein; Neuroblast differentiation-associated protein AHNAK

Desmoyokin (AHNAK)
CCC J661
HGNC 347
MGI 1316648
PubMed 8408266
RGD 619779
UniProt Q09666
The first of these genes identified encoded the cell surface protein CD44, an integral membrane glycoprotein that is the principal receptor for hyaluronate on the cell surface. A second gene, originally designated PM227, attracted their attention because its expression appeared to be coordinated with that of CD44. The amino acid sequence of AHNAK suggested secondary structure with a periodicity of 2.33 residues per turn. Individual chains could associate to form a 7- or 8-stranded barrel. The resulting structure would be a polyionic rod with length as great as 1.2 microns. Preliminary evidence indicated that the protein resides predominantly within the nucleus, but no function had been discerned. The highly conserved repeated elements were, for the most part, 128 amino acids long.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ661Hu01 Recombinant Desmoyokin (AHNAK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ661Hu01 Polyclonal Antibody to Desmoyokin (AHNAK) WB; IHC; ICC; IP.
MAJ661Hu21 Monoclonal Antibody to Desmoyokin (AHNAK) WB; IHC; ICC; IP.
Assay Kits SEJ661Hu ELISA Kit for Desmoyokin (AHNAK) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Desmoyokin (AHNAK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Desmoyokin (AHNAK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Desmoyokin (AHNAK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Desmoyokin (AHNAK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Desmoyokin (AHNAK) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Desmoyokin (AHNAK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Desmoyokin (AHNAK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Desmoyokin (AHNAK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Desmoyokin (AHNAK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Desmoyokin (AHNAK) ELISA Kit Customized Service Offer
  1. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure."Proc. Natl. Acad. Sci. U.S.A. 89:5472-5476(1992) [PubMed] [Europe PMC] [Abstract]
  4. ErratumProc. Natl. Acad. Sci. U.S.A. 90:4328-4328(1993)
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  7. "AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration."FASEB J. 21:732-742(2007) [PubMed] [Europe PMC] [Abstract]
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  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  17. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  18. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  19. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  20. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]