Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2)

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ALPG; GCAP; ALP-1; Alkaline phosphatase Nagao isozyme; Germ cell alkaline phosphatase; Placental alkaline phosphatase-like

Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2)
Cloning and sequencing of the placental alkaline phosphatase, intestinal alkaline phosphatase, and germ-cell alkaline phosphatase genes indicate a high degree of homology; in particular, 98% amino acid sequence identity has been demonstrated between placental and germ-cell forms of the enzyme.
ALPPL1 encodes the classic heat-stabile placental alkaline phosphatase; ALPPL2 is closely related to the first, and may encode the so-called placental ALP-like enzyme of the testis and thymus; the third member of this gene family, the intestinal ALP gene, encodes intestinal alkaline phosphatase. The expression of the intestinal and placental genes is highly tissue-specific in spite of nearly 90% sequence similarity within their exons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ649Hu01 Recombinant Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ649Hu01 Polyclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) WB; IHC; ICC; IP.
LAJ649Hu71 Biotin-Linked Polyclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) WB; IHC; ICC.
MAJ649Hu21 Monoclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) WB; IHC; ICC; IP.
PAJ649Hu02 Polyclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) WB; IHC; ICC; IP.
Assay Kits SEJ649Hu ELISA Kit for Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ649Mu01 Recombinant Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) ELISA Kit Customized Service Offer
  1. "Seminoma-derived Nagao isozyme is encoded by a germ-cell alkaline phosphatase gene."Proc. Natl. Acad. Sci. U.S.A. 85:3024-3028(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of the germ cell alkaline phosphatase gene in human choriocarcinoma cells."J. Biol. Chem. 264:12611-12619(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular cloning of complementary DNAs encoding alkaline phosphatase in human colon cancer cells."Cancer Res. 50:1085-1091(1990) [PubMed] [Europe PMC] [Abstract]
  4. "Expression of a Nagao-type, phosphatidylinositol-glycan anchored alkaline phosphatase in human choriocarcinomas."Cancer Res. 50:3956-3962(1990) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases."Gene 60:267-276(1987) [PubMed] [Europe PMC] [Abstract]
  9. "5' nucleotide sequence of a putative human placental alkaline phosphatase-like gene."Nucleic Acids Res. 16:5694-5694(1988) [PubMed] [Europe PMC] [Abstract]