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ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1)

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ARF1GAP; ARF1-directed GTPase-activating protein

ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1)
CCC J619
HGNC 15852
MGI 2183559
PubMed 22423108
RGD 708452
UniProt Q8N6T3
Wiki ARFGAP1
ARFGAP1 is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
It encodes a deduced 45-kD protein. The catalytic domain of rat Arfgap1 resides within the first 130 to 140 amino acids and contains the essential zinc finger structure.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for ADP Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) ELISA Kit Customized Service Offer
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  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of the ARFGAP domain of human ARFGAP1."Submitted (FEB-2009) to the PDB data bank