BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI)
[Edit]NMA; Non-metastatic gene A protein; Putative transmembrane protein NMA
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By subtractive hybridization screening of melanoma cell lines of different metastatic potential, Degen et al. (1996) isolated a cDNA encoding a 260-amino acid protein designated NMA. Unlike calcyclin and thymosin-beta-10, which are expressed in highly metastatic lines, NMA and NMB are expressed in poorly metastatic melanoma cell lines. The predicted NMA protein contains a signal sequence and a transmembrane domain. Northern blot analysis revealed that expression of NMA was high in melanocytes and in 3 of 4 melanoma metastases with strong pigmentation, but low or absent in 7 other metastases. Its expression is also high in kidney medulla, placenta, and spleen but low in kidney cortex, liver, prostate, and gut. It is not expressed in lung, normal skin tissue, or muscle.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ566Hu01 | Recombinant BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAJ566Hu01 | Polyclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | WB; IHC; ICC; IP. |
MAJ566Hu21 | Monoclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | WB; IHC; ICC; IP. | |
Assay Kits | SEJ566Hu | ELISA Kit for BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for BMP And Activin Membrane Bound Inhibitor Homolog (BAMBI) | ELISA Kit Customized Service Offer |
- "Expression of nma, a novel gene, inversely correlates with the metastatic potential of human melanoma cell lines and xenografts."Int. J. Cancer 65:460-465(1996) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]