Calcium Regulated Heat Stable Protein 1 (CARHSP1)

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CRHSP-24; CSDC; Calcium-regulated heat-stable protein of 24 kDa

Calcium Regulated Heat Stable Protein 1 (CARHSP1)
CARHSP1 protein contains 147 amino acids and is composed of nearly 14% proline. It is ubiquitously expressed and may play a common role in calcium mediated signal transduction.
This protein was expressed as an N-terminal His-tag fusion protein using Escherichia coli, and purified using Immobilized Metal Ion Affinity Chromatography. In some cases, smaller protein fragments may be present in addition to the intended expression product as a result of premature termination during translation in E. coli and subsequent co-purification via the His-tag. In some cases purified proteins run at a molecular weight different to the theoretically calculated molecular weight. This may be as a result of unequally distributed charges in the amino acid sequence.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calcium Regulated Heat Stable Protein 1 (CARHSP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calcium Regulated Heat Stable Protein 1 (CARHSP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calcium Regulated Heat Stable Protein 1 (CARHSP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calcium Regulated Heat Stable Protein 1 (CARHSP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calcium Regulated Heat Stable Protein 1 (CARHSP1) ELISA Kit Customized Service Offer
  1. "Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells."J. Biol. Chem. 273:22738-22744(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL."Biochem. J. 389:775-783(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes."Mol. Cell. Biol. 31:277-286(2011) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Structure-functional analyses of CRHSP-24 plasticity and dynamics in oxidative stress response."J. Biol. Chem. 286:9623-9635(2011) [PubMed] [Europe PMC] [Abstract]