Cingulin Like Protein 1 (CGNL1)

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JACOP, paracingulin; junction-associated coiled-coil protein

Cingulin Like Protein 1 (CGNL1)
By sequencing clones obtained from a size-fractionated fetal brain cDNA library, Nagase et al. (2000) cloned a partial CGNL1 cDNA, which they designated KIAA1749. RT-PCR followed by ELISA detected high expression in smooth muscle, spleen, testis, fetal brain, and the amygdala, corpus callosum, cerebellum, thalamus, and subthalamic nucleus of adult brain.the regulatory regions upstream of the CGNL1 and TMOD3 promoters are similar.
The mouse homolog of CGNL1 has been designated JACOP (junction-associated coiled-coil protein). JACOP is recruited to the junctional complex in epithelial cells and to cell-cell contacts in fibroblasts. It has been suggested that JACOP is involved in anchoring cell-cell contacts to actin-based cytoskeletons within cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cingulin Like Protein 1 (CGNL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cingulin Like Protein 1 (CGNL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cingulin Like Protein 1 (CGNL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cingulin Like Protein 1 (CGNL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cingulin Like Protein 1 (CGNL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cingulin Like Protein 1 (CGNL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cingulin Like Protein 1 (CGNL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cingulin Like Protein 1 (CGNL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cingulin Like Protein 1 (CGNL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cingulin Like Protein 1 (CGNL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cingulin Like Protein 1 (CGNL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cingulin Like Protein 1 (CGNL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cingulin Like Protein 1 (CGNL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cingulin Like Protein 1 (CGNL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cingulin Like Protein 1 (CGNL1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene."N. Engl. J. Med. 348:1855-1865(2003) [PubMed] [Europe PMC] [Abstract]
  5. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]