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Chromatin Assembly Factor 1, Subunit B (CHAF1B)

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CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; MPHOSPH7; MPP7; M-Phase Phosphoprotein 7; Chromatin Assembly Factor I,p60 subunit; M-phase phosphoprotein 7

Chromatin Assembly Factor 1, Subunit B (CHAF1B)
CCC J447
HGNC 1911
MGI 1314881
PubMed 7600578
RGD 1307634
UniProt Q13112
Wiki CHAF1B
CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. The predicted 559-amino acid protein belongs to the WD (tryptophan-aspartate), or transducin, family. These proteins are generally characterized by 4 to 8 copies of a repeat of approximately 40 residues that often ends with a WD sequence (p60 has 7 copies of the motif). The p60 subunit also has a PEST (proline-glutamic acid-serine-threonine) box at its C terminus that is associated with proteins of short half-lives.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Assembly Factor 1, Subunit B (CHAF1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Assembly Factor 1, Subunit B (CHAF1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Assembly Factor 1, Subunit B (CHAF1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Assembly Factor 1, Subunit B (CHAF1B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ447Mu01 Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B) Positive Control; Immunogen; SDS-PAGE; WB.
RPJ447Mu02 Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ447Mu01 Polyclonal Antibody to Chromatin Assembly Factor 1, Subunit B (CHAF1B) WB; IHC; ICC; IP.
PAJ447Mu02 Polyclonal Antibody to Chromatin Assembly Factor 1, Subunit B (CHAF1B) WB; IHC; ICC; IP.
Assay Kits SEJ447Mu ELISA Kit for Chromatin Assembly Factor 1, Subunit B (CHAF1B) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chromatin Assembly Factor 1, Subunit B (CHAF1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chromatin Assembly Factor 1, Subunit B (CHAF1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chromatin Assembly Factor 1, Subunit B (CHAF1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chromatin Assembly Factor 1, Subunit B (CHAF1B) ELISA Kit Customized Service Offer
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  2. "The DNA sequence of human chromosome 21." Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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  9. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  16. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]