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UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1)

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UGTR; HUGT1; GT; UGCGL1; UGGT; UGT1; UDP-glucose ceramide glucosyltransferase-like 1

UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1)
CCC J269
HGNC 15663
MGI 2443162
PubMed 23864712
RGD 619710
UniProt Q9NYU2
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
The assembled full-length HUGT1 cDNA encodes a deduced 1,555-amino acid protein with a predicted ER-targeting signal sequence, ER retrieval signal, 3 N-glycosylation sites, and 2 disulfide loops. HUGT1 shares 55% sequence identity with HUGT2 and 31 to 45% identity with Drosophila, C. elegans, and S. pombe homologs. Northern blot analysis detected 3 HUGT1 transcripts of 5.7, 8, and 10.6 kb in pancreas, heart, brain, placenta, lung, liver, skeletal muscle, and kidney.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ269Hu01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAJ269Hu21 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAJ269Hu01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB
Assay Kits SEJ269Hu ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) ELISA Kit Customized Service Offer
  1. "Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity."Biochemistry 39:2149-2163(2000) [PubMed] [Europe PMC] [Abstract].
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract].
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."PLoS Genet. 9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]