DLL4 is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
The predicted 685-amino acid DLL4 protein exhibits all of the hallmarks of the Delta family of Notch ligands. It has an extracellular region containing 8 EGF-like repeats and a DSL domain involved in Notch binding, as well as a transmembrane domain and a cytoplasmic tail that lacks catalytic motifs. Human DLL4 shares 87% amino acid sequence identity with mouse Dll4. Northern blot analysis of mouse tissues detected highest Dll4 expression in lung, followed by heart, kidney, skeletal muscle, and brain; Dll4 expression was barely detectable in spleen and testis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ256Hu01 | Recombinant Delta Like Protein 4 (dLL4) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAJ256Hu01 | Polyclonal Antibody to Delta Like Protein 4 (dLL4) | WB; IHC; ICC; IP. |
MAJ256Hu21 | Monoclonal Antibody to Delta Like Protein 4 (dLL4) | WB; IHC; ICC; IP. | |
Assay Kits | SEJ256Hu | ELISA Kit for Delta Like Protein 4 (dLL4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Delta Like Protein 4 (dLL4) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Delta Like Protein 4 (dLL4) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Delta Like Protein 4 (dLL4) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Delta Like Protein 4 (dLL4) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Delta Like Protein 4 (dLL4) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPJ256Ra01 | Recombinant Delta Like Protein 4 (dLL4) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPJ256Ra02 | Recombinant Delta Like Protein 4 (dLL4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAJ256Ra01 | Polyclonal Antibody to Delta Like Protein 4 (dLL4) | WB; IHC; ICC; IP. |
PAJ256Ra02 | Polyclonal Antibody to Delta Like Protein 4 (dLL4) | WB; IHC; ICC; IP. | |
LAJ256Ra71 | Biotin-Linked Polyclonal Antibody to Delta Like Protein 4 (dLL4) | WB; IHC; ICC. | |
Assay Kits | SEJ256Ra | ELISA Kit for Delta Like Protein 4 (dLL4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis."Circ. Res. 107:592-601(2010) [PubMed] [Europe PMC] [Abstract]