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Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3)

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CD39L3; HB6; NTPDase-3; CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-apyrase 3

Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3)
CCC J153
HGNC 3365
MGI 1321386
PubMed 17868657
RGD 631326
UniProt O75355
Wiki ENTPD3
ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases. The catabolism of extracellular nucleotides is mediated by several types of ectonucleotidases, including the divalent cation-dependent E-type nucleotidases (NTPases), such as CD39 .
The predicted 529-amino acid CD39L3 protein contains all 4 apyrase-conserved regions (ACRs) characteristic of NTPases and 2 potential transmembrane segments at the N- and C-terminal ends. Northern blot analysis revealed that CD39L3 is expressed as an approximately 3-kb mRNA in most tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Polyclonal Antibody Customized Service Offer
Assay Kits SEJ153Hu ELISA Kit for Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ectonucleoside Triphosphate Diphosphohydrolase 3 (ENTPD3) ELISA Kit Customized Service Offer
  1. "The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster."Genomics 50:357-367(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning, sequencing, and expression of a human brain ecto-apyrase related to both the ecto-ATPases and CD39 ecto-apyrases."Biochim. Biophys. Acta 1386:65-78(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Mutagenesis of two conserved tryptophan residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase."Biochemistry 38:5849-5857(1999) [PubMed] [Europe PMC] [Abstract]
  7. "Site-directed mutagenesis of human nucleoside triphosphate diphosphohydrolase 3: the importance of residues in the apyrase conserved regions."Biochemistry 40:3943-3950(2001) [PubMed] [Europe PMC] [Abstract]
  8. "Characterization of disulfide bonds in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): implications for NTPDase structural modeling."Biochemistry 44:8998-9012(2005) [PubMed] [Europe PMC] [Abstract]