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Exosome Component 1 (EXOSC1)

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CGI-108; CSL4; Csl4p; SKI4; Ski4p; hCsl4p; p13; CSL4 Exosomal Core Protein Homolog; Exosome complex component CSL4

Exosome Component 1 (EXOSC1)
CCC J126
HGNC 17286
MGI 1913833
PubMed 11812149
UniProt Q9Y3B2
Wiki EXOSC1
EXOSC1encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
The mammalian exosome is required for rapid degradation of ARE-containing RNAs but not for poly(A) shortening. the mammalian exosome does not recognize ARE-containing RNAs on its own. ARE recognition required certain ARE-binding proteins that could interact with the exosome and recruit it to unstable RNAs, thereby promoting their rapid degradation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Exosome Component 1 (EXOSC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Exosome Component 1 (EXOSC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Exosome Component 1 (EXOSC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Exosome Component 1 (EXOSC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Exosome Component 1 (EXOSC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Exosome Component 1 (EXOSC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Exosome Component 1 (EXOSC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Exosome Component 1 (EXOSC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Exosome Component 1 (EXOSC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Exosome Component 1 (EXOSC1) ELISA Kit Customized Service Offer
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