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F-Box And Leucine Rich Repeat Protein 3 (FBXL3)

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FBL3; FBL3A; FBXL3A; F-box/LRR-repeat protein 3A

F-Box And Leucine Rich Repeat Protein 3 (FBXL3)
CCC J121
HGNC 13599
MGI 1354702
PubMed 23503662
RGD 1305660
UniProt Q9UKT7
Wiki FBXL3
FBXL3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box And Leucine Rich Repeat Protein 3 (FBXL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box And Leucine Rich Repeat Protein 3 (FBXL3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ121Mu01 Recombinant F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Positive Control; Immunogen; SDS-PAGE; WB.
RPJ121Mu02 Recombinant F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ121Mu01 Polyclonal Antibody to F-Box And Leucine Rich Repeat Protein 3 (FBXL3) WB; IHC; ICC; IP.
PAJ121Mu02 Polyclonal Antibody to F-Box And Leucine Rich Repeat Protein 3 (FBXL3) WB; IHC; ICC; IP.
Assay Kits SEJ121Mu ELISA Kit for F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F-Box And Leucine Rich Repeat Protein 3 (FBXL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F-Box And Leucine Rich Repeat Protein 3 (FBXL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for F-Box And Leucine Rich Repeat Protein 3 (FBXL3) ELISA Kit Customized Service Offer
  1. "Identification of a family of human F-box proteins."Curr. Biol. 9:1177-1179(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins."Science 316:900-904(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm."Cell 152:1091-1105(2013) [PubMed] [Europe PMC] [Abstract]