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Fructosamine-3-Kinase Related Protein (FN3KRP)

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FN3KL

Fructosamine-3-Kinase Related Protein (FN3KRP)
CCC J093
HGNC 25700
MGI 2679256
PubMed 18637789
RGD 1304570
UniProt Q9HA64
Wiki FN3KRP
FN3KRP and FN3K protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition.
The deduced 309-amino acid protein has a calculated molecular mass of 34.4 kD and shares 88% identity with mouse Fn3krp. Like FN3K, FN3KRP has an HGDxxxxN motif that is also found in aminoglycoside kinases. Northern blot analysis detected Fn3krp expression in all mouse tissues examined except intestinal mucosa. Highest expression was in bone marrow, brain, spleen, and kidney.FN3KRP is a ketosamine 3-kinase with a substrate specificity distinct from that of FN3K.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fructosamine-3-Kinase Related Protein (FN3KRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fructosamine-3-Kinase Related Protein (FN3KRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fructosamine-3-Kinase Related Protein (FN3KRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fructosamine-3-Kinase Related Protein (FN3KRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fructosamine-3-Kinase Related Protein (FN3KRP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fructosamine-3-Kinase Related Protein (FN3KRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fructosamine-3-Kinase Related Protein (FN3KRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fructosamine-3-Kinase Related Protein (FN3KRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fructosamine-3-Kinase Related Protein (FN3KRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fructosamine-3-Kinase Related Protein (FN3KRP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fructosamine-3-Kinase Related Protein (FN3KRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fructosamine-3-Kinase Related Protein (FN3KRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fructosamine-3-Kinase Related Protein (FN3KRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fructosamine-3-Kinase Related Protein (FN3KRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fructosamine-3-Kinase Related Protein (FN3KRP) ELISA Kit Customized Service Offer
  1. "A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines."Diabetes 52:2888-2895(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Fructosamine 3-kinase-related protein and deglycation in human erythrocytes."Biochem. J. 382:137-143(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]