Luciferase MDA-MB-231 Triple-negative Breast Cancer Cells (MDA-MB-231-Luc)

MDA-MB-231-Luc cell line is a human breast cancer cell line that has been modified to express the firefly luciferase reporter gene. This luciferase-expressing cell line allows researchers to monitor tumor growth and metastasis in vivo by measuring the bioluminescent signal emitted by the luciferase enzyme.

MDA-MB-231 cell line is a triple-negative breast cancer cell line derived from an invasive ductal carcinoma. These cells are commonly used in cancer research to investigate the biology of aggressive breast cancer subtypes and to test potential therapeutic interventions.

The addition of the luciferase reporter gene to MDA-MB-231 cells enables non-invasive imaging of tumor growth and metastasis in animal models. By administering the substrate luciferin and imaging the bioluminescent signal emitted by the luciferase-expressing cells, researchers can track the progression of cancer growth, assess response to treatment, and evaluate the efficacy of experimental therapies.