Nucleus Pulposus Cells (NPC)
[Edit]An intervertebral discs consist of an outer fibrous ring, the anulus fibrosus disci intervertebralis, which surrounds an inner gel-like center, the nucleus pulposus.The nucleus pulposus of the disc functions to distribute hydraulic pressure in all directions within each intervertebral disc under compressive loads.
Nucleus pulposus cells (NPC) reside in an environment that has a limited vascular supply and generate energy through anaerobic glycolysis.Results indicate that normoxic stabilization of HIF-1alpha is a metabolic adaptation of nucleus pulposus cells to a unique oxygen-limited microenvironment. The study confirmed that HIF-1alpha can be used as a phenotypic marker of nucleus pulposus cells.Nucleus pulposus cells provide an in vitro model for the study of cellular and molecular events involved in disc degeneration, tissue engineering and cell therapy for spine disc disorders.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | CSI113Hu01 | Primary Human Nucleus Pulposus Cells (NPC) | Primary Cells |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | n/a | Medium for Nucleus Pulposus Cells (NPC) (If Necessary) | Cell Culture Medium Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | CSI113Mu01 | Primary Mouse Nucleus Pulposus Cells (NPC) | Primary Cells |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | n/a | Medium for Nucleus Pulposus Cells (NPC) (If Necessary) | Cell Culture Medium Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | CSI113Ra01 | Primary Rat Nucleus Pulposus Cells (NPC) | Primary Cells |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | MSI113Ra11 | Medium for Rat Nucleus Pulposus Cells (NPC) | Used for cluture of Rat Nucleus Pulposus Cells (NPC) |
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | CSI113Rb01 | Primary Rabbit Nucleus Pulposus Cells (NPC) | Primary Cells |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | MSI113Rb11 | Medium for Rabbit Nucleus Pulposus Cells (NPC) | Medium for Rabbit Nucleus Pulposus Cells |
Organism species: Canis familiaris; Canine (Dog)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | CSI113Ca01 | Primary Canine Nucleus Pulposus Cells (NPC) | Primary Cells |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | MSI113Ca11 | Medium for Canine Nucleus Pulposus Cells (NPC) | Medium for Canine Nucleus Pulposus Cells |
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | n/a | Nucleus Pulposus Cells (NPC) | Primary Cells Customized Service Offer |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | n/a | Medium for Nucleus Pulposus Cells (NPC) (If Necessary) | Cell Culture Medium Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | n/a | Nucleus Pulposus Cells (NPC) | Primary Cells Customized Service Offer |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | n/a | Medium for Nucleus Pulposus Cells (NPC) (If Necessary) | Cell Culture Medium Customized Service Offer |
Organism species: Capra hircus; Caprine (Goat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Cells | CSI113Cp01 | Primary Caprine Nucleus Pulposus Cells (NPC) | For research use only. It is not approved for human or animal use, or for applications in in vitro diganostic procedures. |
Extracts | n/a | Extract of Nucleus Pulposus Cells (NPC) | Total Protein/DNA/RNA Extract Customized Service Offer |
Mediums | MSI113Cp11 | Medium for Caprine Nucleus Pulposus Cells (NPC) | Medium for Caprine Nucleus Pulposus Cells |