Renal Cortical Epithelial Cells (RCEC)

Renal cortical epithelial cells (RCEC) are located at the sites of various congenital, metabolic and inflammatory diseases.Renal cortical epithelial cells  play a key role in renal function. They absorb almost all of the glucose and amino acids in the glomerular filtrate, and causes other non nutrients to be excreted in the urine. Renal epithelial cells can produce inflammatory mediators such as cytokines or chemokines, such as IL-8, which can affect and mediate leukocyte chemotaxis, which is involved in the process of acute inflammation. Renal epithelial cells express IL-2Rα and MHC II antigens in the inflammatory process, indicating that these cells are involved in the pathogenesis of immune-induced renal injury.