≡

Grainyhead Like Protein 1 (GRHL1)

[Edit]

LBP-32; MGR; TFCP2L2; Transcription Factor CP2-Like 2; Mammalian grainyhead; Transcription factor CP2-like 2; Transcription factor LBP-32

Grainyhead Like Protein 1 (GRHL1)
CCC H965
HGNC 17923
MGI 2182540
RGD 1305735
UniProt Q9NZI5
GRHL1 encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development.
Huang and Miller (2000) cloned GRHL1, which they designated LBP32. The deduced 618-amino acid protein has a calculated molecular mass of 68 kD. RT-PCR followed by Southern blot analysis detected prominent expression of LBP32 in the JEG-3 cell line only, with little to no expression in human HepG2, NCI-H295A, and HeLa cell lines, human adrenal tissue, and monkey COS-1 cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Grainyhead Like Protein 1 (GRHL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Grainyhead Like Protein 1 (GRHL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Grainyhead Like Protein 1 (GRHL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Grainyhead Like Protein 1 (GRHL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Grainyhead Like Protein 1 (GRHL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Grainyhead Like Protein 1 (GRHL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Grainyhead Like Protein 1 (GRHL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Grainyhead Like Protein 1 (GRHL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Grainyhead Like Protein 1 (GRHL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Grainyhead Like Protein 1 (GRHL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Grainyhead Like Protein 1 (GRHL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Grainyhead Like Protein 1 (GRHL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Grainyhead Like Protein 1 (GRHL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Grainyhead Like Protein 1 (GRHL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Grainyhead Like Protein 1 (GRHL1) ELISA Kit Customized Service Offer
  1. "Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc."J. Biol. Chem. 275:2852-2858(2000) [PubMed] [Europe PMC] [Abstract]
  2. "A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead."Mech. Dev. 114:37-50(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The identification and characterization of human sister-of-mammalian grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors."Biochem. J. 370:953-962(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Perturbed desmosomal cadherin expression in grainy head-like 1-null mice."EMBO J. 27:886-897(2008) [PubMed] [Europe PMC] [Abstract]