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Major Histocompatibility Complex Binding Protein 2 (MBP2)

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HIVEP2; HIV-EP2; MIBP1; ZNF40B; ZAS2; Schnurri-2; MHC Binding Protein 2; Human Immunodeficiency Virus Type I Enhancer Binding Protein 2; c-Myc Intron Binding Protein 1

Major Histocompatibility Complex Binding Protein 2 (MBP2)
CCC H904
HGNC 4921
MGI 1338076
PubMed 11161801
RGD 61988
UniProt P31629
Wiki HIVEP2
Members of the ZAS family, such as ZAS2 (HIVEP2), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb .
The deduced 1,833-amino acid protein has a calculated molecular mass of 202.1 kD. Northern blot analysis detected a 9.5-kb transcript in a human T-cell line and in some tumor cell lines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Binding Protein 2 (MBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Binding Protein 2 (MBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Binding Protein 2 (MBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Binding Protein 2 (MBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Binding Protein 2 (MBP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Binding Protein 2 (MBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Binding Protein 2 (MBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Binding Protein 2 (MBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Binding Protein 2 (MBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Binding Protein 2 (MBP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Binding Protein 2 (MBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Binding Protein 2 (MBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Binding Protein 2 (MBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Binding Protein 2 (MBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Binding Protein 2 (MBP2) ELISA Kit Customized Service Offer
  1. "HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1."J. Biol. Chem. 266:8590-8594(1991) [PubMed] [Europe PMC] [Abstract]
  2. "Structure and expression of MBP-2: a 275 kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class 1 genes."Proc. Natl. Acad. Sci. U.S.A. 89:8971-8975(1992) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties."Proc. Natl. Acad. Sci. U.S.A. 87:8707-8710(1990) [PubMed] [Europe PMC] [Abstract]
  5. "Activation of somatostatin receptor II expression by transcription factors MIBP1 and SEF-2 in the murine brain."Mol. Cell. Biol. 19:3736-3747(1999) [PubMed] [Europe PMC] [Abstract]
  6. "Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."Proteomics 7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]