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Ubiquitin Associated Domain Containing Protein 1 (UBAC1)

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GBDR1; UBADC1; KPC2; E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting complex protein 2

Ubiquitin Associated Domain Containing Protein 1 (UBAC1)
CCC H852
HGNC 30221
MGI 1920995
PubMed 10857748
RGD 1359542
UniProt Q9BSL1
Wiki UBAC1
The deduced 404-amino acid protein has a calculated molecular mass of about 44.4 kD. GBDR1 contains a C-terminal helix-loop-helix motif and an SRC homology-3 (SH3) domain. It has several putative phosphorylation sites, including 8 CK2 sites, as well as 1 N-glycosylation site and 2 N-myristoylation sites. The 5-prime untranslated region of the transcript contains a CpG island, and the 3-prime region contains 2 mRNA instability motifs.
Cell fractionation revealed GBDR1 in the membrane fraction, and detergent treatment indicated that GBDR1 associates with nuclear membranes. In HMVECs, GBDR1 showed a punctate cytoplasmic distribution and a variable number of nuclear

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Associated Domain Containing Protein 1 (UBAC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Associated Domain Containing Protein 1 (UBAC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Associated Domain Containing Protein 1 (UBAC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Associated Domain Containing Protein 1 (UBAC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ubiquitin Associated Domain Containing Protein 1 (UBAC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ubiquitin Associated Domain Containing Protein 1 (UBAC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquitin Associated Domain Containing Protein 1 (UBAC1) ELISA Kit Customized Service Offer
  1. "Identification of a glialblastoma cell differentiation factor-related gene mRNA in human microvascular endothelial cells."Genomics 65:243-252(2000) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase."Nat. Cell Biol. 6:1229-1235(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase."J. Biol. Chem. 280:17694-17700(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  8. "Solution structure of the first UBA domain in the human ubiquitin associated domain containing 1 (UBADC1)."Submitted (JUN-2006) to the PDB data bank