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Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1)

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XLKD1; CRSBP-1; HAR; Extracellular Link Domain Containing 1; Hyaluronic acid receptor; Cell surface retention sequence-binding protein 1

Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1)
CCC H848
HGNC 14687
MGI 2136348
PubMed 11377291
RGD 1310864
UniProt Q9Y5Y7
Wiki LYVE1
LYVE1 encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE-1 is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental purposes.
Sequence analysis predicted that the 322-amino acid type I integral membrane glycoprotein is 41% similar to CD44. LYVE1 contains a leader peptide; a 212-residue extracellular domain with 7 cysteine residues, a serine/threonine-rich region, and 2 potential N-linked glycosylation sites; a 21-amino acid transmembrane domain; and a 63-residue cytoplasmic tail.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH848Mu01 Recombinant Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH848Mu01 Polyclonal Antibody to Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) ELISA Kit Customized Service Offer
  1. "LYVE-1, a new homologue of the CD44 glycoprotein is a lymph-specific receptor for hyaluronan."J. Cell Biol. 144:789-801(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]