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Integrator Complex Subunit 1 (INTS1)

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INT1; NET28

Integrator Complex Subunit 1 (INTS1)
CCC H801
HGNC 24555
MGI 1915760
PubMed 23288851
UniProt Q8N201
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).
By sequencing clones obtained from a size-fractionated adult brain cDNA library, Nagase et al. (2000) cloned INTS1, which they designated KIAA1440. The deduced protein contains 1,377 amino acids. RT-PCR ELISA detected highest expression in whole adult brain, with moderate to high expression in all other adult and fetal tissues and all specific brain regions examined.By SDS-PAGE of proteins that copurified with INTS11 (CPSF3L) in HEK293 cells, Baillat et al. (2005) identified INTS1 as a subunit of the Integrator complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Integrator Complex Subunit 1 (INTS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Integrator Complex Subunit 1 (INTS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Integrator Complex Subunit 1 (INTS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Integrator Complex Subunit 1 (INTS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrator Complex Subunit 1 (INTS1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Integrator Complex Subunit 1 (INTS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Integrator Complex Subunit 1 (INTS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Integrator Complex Subunit 1 (INTS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Integrator Complex Subunit 1 (INTS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Integrator Complex Subunit 1 (INTS1) ELISA Kit Customized Service Offer
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