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Late Cornified Envelope Like Proline Rich Protein 1 (LELP1)

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Novel small proline-rich protein

Late Cornified Envelope Like Proline Rich Protein 1 (LELP1)
CCC H748
HGNC 32046
MGI 1916582
PubMed 15854049
UniProt Q5T871
By searching for genes in a region of chromosome 1q21 associated with atopic dermatitis (ATOD2), Sharma et al. (2007) identified LELP1.
By genomic sequence analysis, Sharma et al. (2007) mapped the LELP1 gene to chromosome 1q21.
Interestingly, locus 5 is 6.2 kb upstream of a late cornified envelope-like proline-rich 1 (LELP1) gene which encodes a novel small proline rich protein. a significant association of rs7534334 (tagged SNP from LELP1) SNP with log10 serum IgE levels in the patient group (P=0.0029). a chromosomal region in close proximity to a novel gene and highlight the need for intense research on LELP1 and other genes close by with respect to atopic disorders.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH748Hu01 Recombinant Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH748Hu01 Polyclonal Antibody to Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) WB; IHC; ICC; IP.
MAH748Hu21 Monoclonal Antibody to Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) WB; IHC; ICC; IP.
Assay Kits SEH748Hu ELISA Kit for Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Late Cornified Envelope Like Proline Rich Protein 1 (LELP1) ELISA Kit Customized Service Offer
  1. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]