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MAP/Microtubule Affinity Regulating Kinase 3 (MARK3)

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CTAK1; KP78; PAR1A; EMK2 Cdc25C-associated protein kinase 1; ELKL motif kinase 2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78

MAP/Microtubule Affinity Regulating Kinase 3 (MARK3)
CCC H685
HGNC 6897
MGI 1341865
PubMed 20733003
RGD 619883
UniProt P27448
Wiki MARK3
CTAK1 was expressed as 3.1- and 3.8-kb transcripts in all human tissues examined; an additional 3.0-kb transcript was observed in heart. The predicted 729-amino acid CTAK1 protein belongs to the AMPK subfamily of protein kinases. Members of this subfamily are characterized by a conserved N-terminal kinase domain, a divergent C-terminal region, and a conserved region of about 40 amino acids at their extreme C-termini, which end with an ELKL (glutamate-leucine-lysine-leucine) domain. CTAK1 protein from HeLa cell lysates resolved as a doublet of approximately 78 and 80 kD in Western blot and immunoprecipitation analyses. Indirect immunofluorescence detected CTAK1 in the cytoplasm but not the nucleus of HeLa cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) CLIA Kit Customized Service Offer
n/a ELISA Kit for MAP/Microtubule Affinity Regulating Kinase 3 (MARK3) ELISA Kit Customized Service Offer
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  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
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  7. "New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases."Mol. Cell. Biol. 26:7086-7102(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids."Cell 143:966-977(2010) [PubMed] [Europe PMC] [Abstract]
  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  17. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]