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Monoacylglycerol-O-acyltransferase 3 (MOGAT3)

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DGAT2L7; DC7; Diacylglycerol O-acyltransferase candidate 7; Diacylglycerol acyltransferase 2-like protein 7; 2-acylglycerol O-acyltransferase 3

Monoacylglycerol-O-acyltransferase 3 (MOGAT3)
CCC H628
HGNC 23249
PubMed 22394502
UniProt Q86VF5
The deduced 341-amino acid protein contains up to 5 predicted transmembrane domains and has a predicted molecular mass of 36 kD. MOGAT3 shares 49%, 44%, and 46% amino acid sequence identity to human DGAT2, MOGAT1, and MOGAT2, respectively. Fluorescence-tagged MOGAT3 expressed in COS-7 cells localized to the endoplasmic reticulum in a reticular staining pattern indistinguishable from that of calnexin .
MOGAT3 mRNA is expressed almost exclusively in the digestive system, with highest expression in the ileum and lower expression in the remaining portions of the lower gastrointestinal tract and liver. MOGAT3 mRNA was not detected in the stomach, esophagus, trachea, or in any other tissues tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Monoacylglycerol-O-acyltransferase 3 (MOGAT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Monoacylglycerol-O-acyltransferase 3 (MOGAT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Monoacylglycerol-O-acyltransferase 3 (MOGAT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Monoacylglycerol-O-acyltransferase 3 (MOGAT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Monoacylglycerol-O-acyltransferase 3 (MOGAT3) ELISA Kit Customized Service Offer
  1. "Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption."J. Biol. Chem. 278:13611-13614(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]