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Myogenic Factor 6 (MYF6)

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MRF4; BHLHC4; Herculin; Class C basic helix-loop-helix protein 4; Muscle-specific regulatory factor 4

Myogenic Factor 6 (MYF6)
CCC H589
HGNC 7566
MGI 97253
PubMed 19453646
RGD 3134
UniProt P23409
Wiki Myf6
MYF6 is a member of the myogenic factors (MYF) family that regulate myogenesis and muscle regeneration. Myogenic factor are basic-helix-loop-helix (bHLH) transcription factors.
This sequence motif is a common feature of all myogenic factors and other regulatory proteins. By a panel of human/rodent somatic hybrid cells lines, Braun et al. (1990) mapped MYF6 to chromosome 12. In situ hybridization suggested close localization to MYF5. When a human genomic library was screened for the MYF6 gene, 2 of the recombinant lambda-phages isolated contained all or parts of both MYF6 and MYF5. Restriction analysis indicated that the MYF6 gene is located upstream of MYF5 in the same orientation, with a distance of about 6.5 kb separating the genes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myogenic Factor 6 (MYF6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myogenic Factor 6 (MYF6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myogenic Factor 6 (MYF6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myogenic Factor 6 (MYF6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myogenic Factor 6 (MYF6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myogenic Factor 6 (MYF6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myogenic Factor 6 (MYF6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myogenic Factor 6 (MYF6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myogenic Factor 6 (MYF6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myogenic Factor 6 (MYF6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myogenic Factor 6 (MYF6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myogenic Factor 6 (MYF6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myogenic Factor 6 (MYF6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myogenic Factor 6 (MYF6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myogenic Factor 6 (MYF6) ELISA Kit Customized Service Offer
  1. "Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12."EMBO J. 9:821-831(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "MYF6 mutations resulting in A112S and A90D substitutions in patients with skeletal or cardiac muscle pathology."Hum. Mutat. 12:220-220(1998)
  5. "Heterozygous myogenic factor 6 mutation associated with myopathy and severe course of Becker muscular dystrophy."Neuromuscul. Disord. 10:572-577(2000) [PubMed] [Europe PMC] [Abstract]