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NAD Kinase (NADK)

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Poly(P)/ATP NAD kinase

NAD Kinase (NADK)
CCC H578
HGNC 29831
MGI 2183149
PubMed 21517775
UniProt O95544
Wiki NADK
kinase (EC 2.7.1.23, NADK) is an enzyme that converts nicotinamide adenine dinucleotide (NAD+) into NADP+, through phosphorylating the NAD+ coenzyme. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined.
The deduced 446-amino acid protein has a calculated molecular mass of 49.2 kD. Northern blot analysis detected a 3.0-kb transcript with high expression in placenta, moderate expression in brain, colon, heart, liver, kidney, lung, spleen, stomach, and testis, and low expression in small intestine. A band of 1.8 kb was detected in several tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH578Hu01 Recombinant NAD Kinase (NADK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH578Hu01 Polyclonal Antibody to NAD Kinase (NADK) WB; IHC; ICC; IP.
MAH578Hu21 Monoclonal Antibody to NAD Kinase (NADK) WB; IHC; ICC; IP.
Assay Kits SEH578Hu ELISA Kit for NAD Kinase (NADK) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NAD Kinase (NADK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NAD Kinase (NADK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NAD Kinase (NADK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NAD Kinase (NADK) CLIA Kit Customized Service Offer
n/a ELISA Kit for NAD Kinase (NADK) ELISA Kit Customized Service Offer
  1. "Structural and functional characterization of human NAD kinase."Biochem. Biophys. Res. Commun. 288:69-74(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Crystal structure of human NAD kinase."Submitted (NOV-2010) to the PDB data bank