Neurogenic Differentiation 4 (NEUROD4)
[Edit]Atoh3; ATH-3; MATH-3; bHLHa4; Mammalian Atonal Homolog 3; Atonal Homolog 3; Class A basic helix-loop-helix protein 4; Neurogenic differentiation factor 4
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Human and mouse NEUROD4 share 88.5% amino acid identity overall and 100% identity within their bHLH regions.NEUROD4 gene contains 2 exons and spans about 10 kb.
Tsuda et al. (1998) stated that mouse Neurod4, which they called Math3, is initially expressed throughout the developing nervous system, then gradually becomes restricted to neural retina. By functional analysis, they identified a proximal region of the Math3 promoter necessary for neuron-specific expression and an upstream region necessary for retinal expression.Lee and Pfaff (2003) showed that Neurod4, which they called NeuroM, and Ngn2 (NEUROG2) actively participated with Isl1 and Lhx3 to specify motor neuron subtype in embryonic chicken spinal cord and in P19 mouse stem cells.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neurogenic Differentiation 4 (NEUROD4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neurogenic Differentiation 4 (NEUROD4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neurogenic Differentiation 4 (NEUROD4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Neurogenic Differentiation 4 (NEUROD4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neurogenic Differentiation 4 (NEUROD4) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neurogenic Differentiation 4 (NEUROD4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neurogenic Differentiation 4 (NEUROD4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neurogenic Differentiation 4 (NEUROD4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Neurogenic Differentiation 4 (NEUROD4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neurogenic Differentiation 4 (NEUROD4) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neurogenic Differentiation 4 (NEUROD4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neurogenic Differentiation 4 (NEUROD4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neurogenic Differentiation 4 (NEUROD4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Neurogenic Differentiation 4 (NEUROD4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neurogenic Differentiation 4 (NEUROD4) | ELISA Kit Customized Service Offer |
- "Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY."Diabetes 49:1955-1957(2000) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]