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Nuclear Factor Related To Kappa B Binding Protein (NFRkB)

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INO80G; DNA-Binding Protein R Kappa B; INO80 Complex Subunit G

Nuclear Factor Related To Kappa B Binding Protein (NFRkB)
CCC H547
HGNC 7802
MGI 2442410
PubMed 22984442
RGD 1310558
UniProt Q6P4R8
Wiki NFRKB
Nuclear factor related to kappa-B-binding protein is a protein encoded by the NFRKB gene.Nuclear factor-kappa-B (NFKB1; NFKB2) binds in vitro to several of the kappa-B regulatory elements found in cellular and viral genes. Another DNA binding protein, R-kappa-B, binds to a related variant of the kappa-B site that regulates interleukin-2 receptor alpha-chain (IL2RA) gene expression, a critical event in T-cell activation.
By Southern blot analysis of a human-mouse somatic cell hybrid panel and in situ hybridization using a fluorescent genomic probe, Adams et al. (1992) mapped the NFRKB gene to 11q24-q25. It was the most telomeric marker identified up to that point on 11q.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH547Hu01 Recombinant Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH547Hu01 Polyclonal Antibody to Nuclear Factor Related To Kappa B Binding Protein (NFRkB) WB; IHC; ICC; IP.
MAH547Hu21 Monoclonal Antibody to Nuclear Factor Related To Kappa B Binding Protein (NFRkB) WB; IHC; ICC; IP.
Assay Kits SEH547Hu ELISA Kit for Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Factor Related To Kappa B Binding Protein (NFRkB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Factor Related To Kappa B Binding Protein (NFRkB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit Customized Service Offer
  1. "Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site."New Biol. 3:1063-1073(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex."J. Biol. Chem. 280:41207-41212(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex."Mol. Cell 31:909-917(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling."J. Biol. Chem. 286:11283-11289(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  15. "Structure of a novel winged-helix like domain from human NFRKB protein."PLoS ONE 7:E43761-E43761(2012) [PubMed] [Europe PMC] [Abstract]