Neuronal PAS Domain Protein 3 (NPAS3)
[Edit]PASD6; bHLHe12; MOP6; Basic-helix-loop-helix-PAS protein MOP6; Class E basic helix-loop-helix protein 12; PAS domain-containing protein 6
![Neuronal PAS Domain Protein 3 (NPAS3)](/upload/item/img/Neuronal-PAS-Domain-Protein-3-(NPAS3)-97525.jpg)
NPAS3 is a brain-enriched transcription factor belonging to the bHLH-PAS superfamily of transcription factors, the members of which carry out diverse functions, including circadian oscillations, neurogenesis, toxin metabolism, hypoxia, and tracheal development. NPAS3 contains basic-helix-loop-helix structural motif and PAS domain, like the other proteins in the superfamily. According to the same study, NPAS1 and NPAS3 disruption leads to reduced expression of reelin, which is also consistently found to be reduced in the brains of human patients with schizophrenia and psychotic bipolar disorder. Among the 49 genomic regions that undergone rapid changes in humans compared with their evolutionary ancestors, NPAS3 was found to be located in the region 21.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neuronal PAS Domain Protein 3 (NPAS3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neuronal PAS Domain Protein 3 (NPAS3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neuronal PAS Domain Protein 3 (NPAS3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neuronal PAS Domain Protein 3 (NPAS3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neuronal PAS Domain Protein 3 (NPAS3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neuronal PAS Domain Protein 3 (NPAS3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neuronal PAS Domain Protein 3 (NPAS3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neuronal PAS Domain Protein 3 (NPAS3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neuronal PAS Domain Protein 3 (NPAS3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neuronal PAS Domain Protein 3 (NPAS3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neuronal PAS Domain Protein 3 (NPAS3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neuronal PAS Domain Protein 3 (NPAS3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neuronal PAS Domain Protein 3 (NPAS3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neuronal PAS Domain Protein 3 (NPAS3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neuronal PAS Domain Protein 3 (NPAS3) | ELISA Kit Customized Service Offer |
- "Disruption of the neuronal PAS3 gene in a family affected with schizophrenia."J. Med. Genet. 40:325-332(2003) [PubMed] [Europe PMC] [Abstract]